Coffee Reduces Risk of Alzheimer's Disease

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Can drinking coffee reduce your risk of developing dementia and Alzheimer’s Disease? According to a study at the University of Kuopio, Finland in collaboration with the Karolinska Institutet in Stockholm, Sweden, and the National Public Health Institute in Helsinki, Finland, the answer is yes.

The January 2009 issue of The Journal of Alzheimer’s Disease (Volume 16:1) reported that the coffee drinking participants involved in a 21-year study had significantly lower incidences.

The consumption of coffee was assessed in three groups: those who drank 0-2 cups; 3-5 cups; and more than 5 cups per day. The study found that coffee drinkers at midlife had lower risk for dementia and Alzheimer’s Disease later in life compared to those drinking no or only little coffee. The lowest risk (65% decreased) was found among those drinking between 3-5 cups of coffee a day.

Perhaps that morning jump-start, afternoon buzz and late night jolt is doing more good than you’d imagined.

Publication: Marjo H. Eskelinen, Tiia Ngandu, Jaakko Tuomilehto, Hilkka Soininen, Miia Kivipelto (2009).

Image: DeaPeaJay


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DISCUSSION

  • Kari Luoto
    December 12th, 2009 at 3:12 PM

    Midlife Coffee and Tea Drinking and the Risk of
    Late-Life Dementia: A Population-Based CAIDE Study
    finds that coffee would prevent dementia, which is
    contrary to the existing medical scientific knowledge.

    Caffeine is known to cause dementia by interrupting the
    normal cycle of apoptosis and neurogenesis in
    hippocampus, by enhancing apoptosis and inhibiting
    neurogenesis. Prolonged use will cause hippocampal atrophy.

    As the altered A-N cycle causes deteriation of
    functions dependant of the normal cycle, this affects
    memory and spatial learning functions, and as the cell
    damage advances, so do the symptoms.

    The data in this study has been interpreted as if the
    biotransformation and cns-based sensitivity to caffeine
    would be homogenous in the entire population. If this
    was the case, the study would, without a doubt, be a
    very strong evidence, supporting the conclusions of the
    research team.

    When taking in consideration known medical scientific
    knowledge about the pharmacological effects of
    caffeine, and their proven connection to dementia, the
    raw data of this study leaves only one possible
    explanation.

    Processes causing dementia may be triggered by various
    reactions between endogenic and exogenic factors.

    Individuals whose body is well protected against
    caffeine induced dementia, are also protected against
    other exogenic triggers, while individuals with an
    endogenous sensitivity to caffeine, may also be
    sensitive to other exogenous triggers.

    This is the only way to get the data of the study to
    match with proved medical scientific knowledge.